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用生化方法测定口腔颌面部恶性肿瘤56例,良性肿瘤47例,并与35例正常人作对照。检测肿瘤患者血清脂质结合唾液酸(LSA),总唾液酸(TSA)的含量。结果:恶性肿瘤组中LSA、TSA高于良性肿瘤组和正常对照组(P<0.01);良性肿瘤组与正常对照组无显著差异(P<0.05);LSA、TSA的值与口腔颌面部恶性肿瘤的TNM分期之间有一定的关系;其含量水平升高或明显下降对判定疗效预后有价值。在鉴别诊断方面有重要意义。
56 cases of oral and maxillofacial malignancy, 47 cases of benign tumor were determined by biochemical methods and compared with 35 normal controls. Tumor patients with serum lipid-bound sialic acid (LSA), total sialic acid (TSA) content. Results: The levels of LSA and TSA in malignant tumor group were significantly higher than those in benign tumor group and normal control group (P <0.01). There was no significant difference between benign tumor group and normal control group (P <0.05) Oral and maxillofacial malignancies TNM staging have a certain relationship; the level of its content or significantly decreased the prognosis of judging the value of prognosis. In the differential diagnosis of great significance.