论文部分内容阅读
目的探讨血清前白蛋白、总胆汁酸、CA125在肝硬化分级中的变化及其临床意义。方法随机选择76例肝硬化患者作为实验组,根据child-pugh肝功能分级积分法分级,32例健康体检人员作为对照组。检测两组血清前白蛋白、总胆汁酸、CA125水平,分析两者与肝功能分级的关系。结果肝硬化患者血清前白蛋白、总胆汁酸、CA125水平与对照组比较,差异有统计学意义(P<0.05)。且肝硬化组组间比较,差异有统计学意义(P<0.05)。结论血清前白蛋白、总胆汁酸及CA125是反映肝损害的灵敏指标,可以较好的反映病情的严重程度。
Objective To investigate the changes and clinical significance of prealbumin, total bile acid and CA125 in the classification of liver cirrhosis. Methods A total of 76 patients with cirrhosis were randomly divided into experimental group, grading by child-pugh liver function grading method and 32 healthy people as control group. Pre-serum albumin, total bile acid, CA125 levels were detected, and the relationship between the two groups and liver function grading was analyzed. Results The serum prealbumin, total bile acid and CA125 levels in patients with cirrhosis were significantly different from those in the control group (P <0.05). The differences between the two groups were statistically significant (P <0.05). Conclusions Pre-serum albumin, total bile acid and CA125 are sensitive indicators of liver damage, which can better reflect the severity of the disease.