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目的：分析评价３ 种肺癌化学治疗方案，指导临床合理用药。方法：采用药物经济学成本－ 效果分析方法。结果：３ 种化疗方案，即ＤＯＡＣ、ＶＰ、ＣＡＰ 中，ＤＯＡＣ 组有效率５４－５ ％ ，１ 个疗程费用为２０ ０８４－１２ 元，有效率每增加１ 个百分点，成本为３６８－５２ 元；ＶＰ组有效率为３７－５ ％ ，１ 个疗程费用为６６ ２３０－０８ 元， 有效率每增加１ 个百分点，成本为１ ７６６－１４ 元；ＣＡＰ 组有效率为３３－３ ％ ，１ 个疗程费用为１８ １６６－６８ 元，有效率每增加１ 个百分点，成本为５４５－５５ 元。ＤＯＡＣ 方案较其余２ 种方案生活质量好。结论：ＤＯＡＣ 方案是３ 种肺癌化学治疗方案中最合理的方案。
Objective: To analyze and evaluate three kinds of lung cancer chemotherapy programs and guide clinical rational drug use. Methods: A pharmacoeconomics cost-effectiveness analysis method was used. Results: In the three chemotherapy regimens, DOAC, VP, and CAP, the DOAC group had an efficiency of 54-5 percent, a course cost of 20 084-12 yuan, and the efficiency increased by 1 percentage point. The cost was 368-52 yuan; The effective rate in the VP group was 37-5 %, the cost of one course was 66 230-08 yuan, and the cost was 1 766-14 yuan for every 1 percentage point increase in efficiency, and 33-3 % for the CAP group, with 1 course of treatment. The cost is 18 166-68 yuan. For every additional percentage point of efficiency, the cost is 545-55 yuan. The DOAC program has better quality of life than the other two programs. Conclusion: The DOAC protocol is the most reasonable of the 3 lung cancer chemotherapy regimens.