在乙氨芴酮(Tilorone)诱导下产生的干扰素除了对多种病毒有抑制作用外,对巨噬细胞有激活作用并能增强抗体的形成。我们用Tilrone进行实验性矽肺治疗时,曾观察到有抑制纤维化病变进展的作用。为了解Tilorone在治疗实验性矽肺中的免疫影响,我们在1980年12月～1982年3月间测定了实验性矽肺体內特异性抗原及溶血素单位和血细胞凝集素滴度。实验结呆表明 Interferon, which is induced by Tilorone, can activate macrophages and enhance the formation of antibodies in addition to its ability to inhibit various viruses. When we performed experimental silicosis treatment with Tilrone, we observed the effect of inhibiting the progression of fibrotic lesions. To understand Tilorone’s immune response in experimental silicosis, we tested experimental silicotic specific antigen and hemolysin units and hemagglutinin titers from December 1980 to March 1982. Experimental results show that