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探讨卵巢恶性肿瘤发生的影响因素。方法应用１∶１配对病例对照研究，收集３所医院妇科收治的恶性卵巢肿瘤患者５２例作为病例组，收集同期住院的非妇产科、非肿瘤、与激素无关的其它女性患者５２例作为对照组，两组间同性别、同民族，一对内年龄相差不超过５岁，对所得资料进行单因素条件Ｌｏｇｉｓｔｉｃ回归分析及多元条件Ｌｏｇｉｓｔｉｃ回归分析。结果有恶性肿瘤家族史、滑石粉暴露为卵巢恶性肿瘤主要的危险因素，而多产、哺乳为主要的保护因素；高促性腺激素水平及低雄激素水平可能与卵巢癌的危险增加有关。结论恶性卵巢肿瘤可能为多种因素综合作用的结果，既与环境因素有关，更与遗传因素、生殖因素和内分泌因素有关。
To explore the influencing factors of ovarian cancer. Methods A 1: 1 matched case-control study was conducted. Fifty-two cases of malignant ovarian tumors were collected from three gynecological hospitals. 52 cases of non-obstetrics and gynecology, non-tumor and other women who were unrelated to hormone were collected as the control group Group, the same sex between the two groups, with the nationality, within a pair of age difference of not more than 5 years old, the information obtained by single factor conditional Logistic regression analysis and multivariate conditional Logistic regression analysis. The results of a family history of malignant tumors, talc exposure is a major risk factor for ovarian cancer, and prolific, lactation as the main protective factors; gonadotropin levels and low androgen levels may be related to the increased risk of ovarian cancer. Conclusions Malignant ovarian tumors may be the result of the combined effect of many factors, which are not only related to environmental factors, but also related to genetic factors, reproductive factors and endocrine factors.