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虽然系统性红斑狼疮(SLE)累及多器官系统,它的头5年死亡率主要取决于肾脏损害的性质和尚不清楚的确定肾脏损害演变率的因素。活组织检查证明有肾小球损害的占50～70％。在确诊的SLE患者中,完全正常的肾脏组织是罕见的。肾活检有弥漫性增殖性肾小球损害的,其5年存活率为20～25％。本文报导活检证实的31例系统性红斑狼疮弥漫性增殖性肾小球肾炎的5年存活率为77.7％,其存活率的改善归功于强的松和苯丁酸氮芥的联合应用及常常重复对该病活动有指导价值的实验室检查。
Although systemic lupus erythematosus (SLE) affects multiple organ systems, its first 5-year mortality mainly depends on the nature of renal impairment and the factors that determine the evolutionary rate of renal damage. Biopsy proved glomerular damage accounted for 50 to 70%. In diagnosed patients with SLE, completely normal kidney tissue is rare. Renal biopsy diffuse proliferative glomerular damage, the 5-year survival rate of 20 to 25%. The biopsy confirmed 31 cases of systemic lupus erythematosus diffuse proliferative glomerulonephritis 5-year survival rate was 77.7%, the improvement of survival due to the combination of prednisone and chlorambucil and often repeated A laboratory test that will guide the activity of the disease.