目的 制定一种只需每日一次的多成分的预防心血管疾病的复方制剂(Polypill),确定其成分和剂量,以减少用药的不良反应,获得最大的预防效果。这个新设想的核心在于,针对心脑血管疾病的4个危险因素同时用药,而且不管其初始水平如何。这4个因素包括低密度脂蛋白胆固醇、血压、血清高半胱氨酸和血小板功能。 Objective To develop a multicomponent multi-component cardiovascular disease prevention compound (Polypill) that can be administered on a daily basis to determine its composition and dosage so as to reduce adverse drug reactions and achieve maximum preventive effect. At the heart of this new vision is the simultaneous administration of four risk factors for cardiovascular and cerebrovascular diseases, regardless of their initial level. These four factors include low density lipoprotein cholesterol, blood pressure, serum homocysteine ​​and platelet function.