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目的探讨大量蛋白尿是否增加子前期母婴严重并发症的发生率。方法对北京大学第四临床医院1990-01-2005-03收治的资料完整的56例子前期患者临床资料进行回顾性分析,按照尿蛋白定量分为24h尿蛋白<5g和24h尿蛋白≥5g组,分析统计严重母婴并发症的发生率,并进行统计学分析。结果两组母婴严重并发症,包括子、胎盘早剥、HELLP综合征、胎死宫内等发生率差异无统计学意义(P>0.05)。结论合并大量蛋白尿不增加子前期患者母婴严重并发症的发生率。单纯依据大量蛋白尿不应作为判断子前期患者预后或选择结束妊娠的主要指标。
Objective To investigate whether a large amount of proteinuria increases the incidence of serious complications of pre-term maternal and neonatal complications in children. Methods A retrospective analysis was performed on the clinical data of 56 cases of preeclampsia patients admitted to the Fourth Clinical Hospital of Peking University from January 1990 to March 2005 and divided into 24 hours urinary protein <5g and 24h urinary protein> , Analysis of the incidence of serious maternal and child complications, and statistical analysis. Results There was no significant difference in the incidence of serious complications of maternal and infant between the two groups, including child moles, placental abruption, HELLP syndrome and intrauterine fetal death (P> 0.05). Conclusions The combination of large amounts of proteinuria does not increase the incidence of serious complications of maternal and neonatal patients. Purely based on a large number of proteinuria should not be used as the prognosis of children to determine the prognosis of children or choose the end of the main indicators of pregnancy.