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目的观察艾司洛尔控制围麻醉期心律失常和高血压的疗效。方法１５例择期手术病人，ＡＳＡ分级Ⅰ～Ⅱ级，围麻醉期经处理，１０～２０ｍｉｎ后心室率仍≥１２０次，首次静注艾司洛尔１ｍｇｋｇ－１，记录用药量，用药后１，３，５，７，１０ｍｉｎ收缩压、舒张压和心率，如６ｍｉｎ未降低达标准，再追加半量。结果用药前心率为１４６次±１９次，用药１ｍｉｎ后明显下降至１１８次±１５次，７ｍｉｎ至最低９８次±１５次，收缩压和舒张压也明显下降。其中５例追加艾司洛尔。结论艾司洛尔是快速、短效的β受体阻滞药，可有效地控制围麻醉期的心率和血压。
Objective To observe the efficacy of esmolol on perioperative arrhythmia and hypertension. Methods Fifteen patients undergoing elective surgery under ASA classification Ⅰ ~ Ⅱ were treated with perioperative anesthesia. The ventricular rate was still ≥120 after 10 ~ 20 min. The first intravenous injection of esmolol 1 mg kg-1 was recorded, 3,5,7,10 min systolic blood pressure, diastolic blood pressure and heart rate, such as 6min did not reduce the standard, and then add half the amount. Results Before treatment, the heart rate was 146 ± 19 times. After 1 minute of treatment, the heart rate decreased significantly to 118 ± 15 times, and the minimum systolic blood pressure and diastolic blood pressure decreased significantly from 7 minutes to 98 times ± 15 times. In 5 cases, esmolol was added. Conclusion Esmolol is a fast and short-acting β-blocker, which can effectively control heart rate and blood pressure during peri-anesthesia.