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1.临床观察证明,在结核杆菌耐药性的发生机制中,发生着一系列的夏杂因素,其中尤以机体的状态、结核病变的性质、在治疗中所使用化学药物的方法,占有特殊的地位。 2.在临床和防治所的条件下,结核分枝杆菌的耐药性常被发现,特别在治疗慢性纤维空洞型肺结核时,耐药性的发生,在1953—1955年几乎占病例的60—70％。 3.由于更合理的使用抗病原制剂(并用投药,疗程较长并继续与其他冶疗措施综合治疗),最近几年,耐药性的发生显著地受到抑制,在新鲜的空洞型病变中,有75％结核杆菌对药物有敏感性。 4.精密测定结核杆菌耐药性的类型和耐药性的程度,对于合理使用抗菌制剂特别在长期疗程时,有重大的意义。
1. Clinical observation shows that in the mechanism of Mycobacterium tuberculosis drug resistance occurs a series of summer factors, including the state of the body, the nature of tuberculosis, the use of chemical drugs in the treatment of possession of special Position. 2. Mycobacterium tuberculosis resistance is often found in clinical and preventive settings, especially in the treatment of chronic fibrous cavitary tuberculosis. In 1953-1955, almost 60- 70%. 3. In the recent years, the development of drug resistance has been significantly inhibited in recent years due to the more rational use of anti-pathogenic agents (in combination with long-term treatment and continued treatment with other therapies). In fresh cavitary lesions , 75% of Mycobacterium tuberculosis are drug sensitive. 4. The precise determination of the type of Mycobacterium tuberculosis and drug resistance, the rational use of antimicrobial agents, especially in the long-term course of treatment, of great significance.