黄荆(Vitex negundo)根的甲醇提取物在海虾致死试验中显示强细胞毒性,其氯仿提取物对脂氧合酶和乙酰胆碱酯酶有显著抑制作用。本次从中分离得到2个新的(1、2)和4个已知的木脂素(3～6)。黄荆根阴干切片后,于甲醇中浸泡10d,重复提取3次,合并提取液,减压回收溶剂。残余物(1.5kg)混 The methanol extract of Vitex negundo root showed strong cytotoxicity in the lethal test of sea shrimp, and its chloroform extract significantly inhibited lipoxygenase and acetylcholinesterase. Two new (1, 2) and 4 known lignans (3-6) were isolated from this time. After being dried and sliced, it was soaked in methanol for 10 days and extracted three times repeatedly. The extracts were combined and the solvent was recovered under reduced pressure. Residue (1.5kg) mixed