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目的 :研究络泰粉针剂对脑缺血的保护作用。方法 :用结扎颈总动脉合并降压法制备脑缺血模型研究络泰粉针剂对动物脑缺血的影响。结果 :络泰粉针剂 (6 0mg/kg ,12 0mg/kg)可使缺血大鼠的脑含水量、脑毛细血管通透性、脑组织缺血损伤程度下降 ;络泰粉针剂 (12 0mg/kg)还能使小鼠耐缺氧能力明显提高。 结论 :络泰粉针剂对脑缺血有保护作用
Objective : To study the protective effect of Luotai injection on cerebral ischemia. METHODS: The cerebral ischemic model was established by ligation of common carotid artery combined with antihypertensive method to study the effect of Luotai injection on cerebral ischemia in animals. RESULTS: Luotai injection (60 mg/kg, 120 mg/kg) decreased cerebral water content, cerebral capillary permeability, and ischemic brain injury in ischemic rats; Luotai injection (12 0 mg) /kg) can also significantly improve the ability of mice to withstand hypoxia. Conclusion : Luotai injection has a protective effect on cerebral ischemia