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目的分析不规则抗体筛查在妊娠期和围生期中的应用价值。方法选取2016年4-12月秦皇岛市妇幼保健院产科门诊就诊的妊娠期、围生期妇女2 880例为研究对象,做ABO、Rh D血型及不规则抗体筛查。结果 2 880例孕妇中不规则抗体筛查阳性率为1.08%;阳性鉴定结果中抗体分布Rh系统占41.94%,其中抗-E占16.13%。≤孕28周孕妇的抗体筛查阳性率为0.90%,孕29~37周阳性率为3.70%,孕38~40周阳性率为0.00%,不同孕周间差异有统计学意义(P<0.01)。抗体筛查阳性孕妇中初产妇的发生率为0.50%,经产妇为1.80%,差异有统计学意义(P<0.01)。结论孕妇尤其是有输血史、妊娠史、剖宫产史的经产妇在妊娠期和围生期做不规则抗体筛查是非常必要的。
Objective To analyze the value of irregular antibody screening during pregnancy and perinatal period. Methods A total of 2880 pregnant and perinatal women were selected as obstetrics and gynecology clinic in Qinhuangdao MCH from April to December in 2016. The ABO and Rh D blood group and irregular antibody screening were selected. Results The positive rate of irregular antibody screening in 2 880 pregnant women was 1.08%. In the positive results, the distribution of antibody was 41.94% in Rh system, of which anti-E accounted for 16.13%. ≤ 28 weeks pregnant women antibody screening positive rate was 0.90%, the positive rate of 29 to 37 weeks pregnant was 3.70%, the positive rate of 38 to 40 weeks of pregnancy was 0.00%, the difference was statistically significant between different gestational weeks (P <0.01 ). The prevalence of primipara in antibody-positive pregnant women was 0.50% and that in maternal women was 1.80%, the difference was statistically significant (P <0.01). Conclusion Pregnant women, especially the history of blood transfusion, pregnancy history, history of cesarean section in pregnant women during pregnancy and perinatal irregular antibody screening is very necessary.