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目的:了解“抗菌药物临床应用专项整治活动”(简称“整治活动”)前后我院门诊抗菌药使用情况,评估“整治活动”对抗菌药临床使用干预的效果。方法:采用回顾性分析,随机抽取实施干预措施前的2011年1～3月及干预后的2012年1～3月门诊处方各2 400张,用合理用药国际指标(SDUIs)和《抗菌药物临床应用指导原则》对抗菌药的使用情况进行调研。结果:干预后,使用抗菌药比例由47.83%下降至28.29%,抗菌药中注射剂的百分率由40.43%下降至25.53%,抗菌药给药途径及品种的选择更为合理。结论:开展“整治活动”对临床合理使用抗菌药的干预效果明显。
OBJECTIVE: To understand the use of antibacterials in outpatient clinics in our hospital before and after the special rectification activities of clinical application of antibacterials, and to evaluate the effect of antibacterials’ clinical intervention on the use of remediation activities. Methods: A retrospective analysis was conducted to randomly select 2 400 outpatient prescriptions from January to March, 2011 and January to March, 2012 before implementation of the intervention measures. The international standards for rational use of drugs (SDUIs) and the “Antibacterials Clinical Application Guidelines ”to investigate the use of antibacterial drugs. Results: After the intervention, the proportion of antibacterials decreased from 47.83% to 28.29%, the percentage of injections in antibacterials decreased from 40.43% to 25.53%, and the choice of antibacterial agents and varieties was more reasonable. Conclusion: To carry out “remediation activities ” effect on the rational use of antibacterial drugs in clinical intervention.