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目的：探讨理智－情绪疗法（ＲＥＴ）、阿米替林、ＲＥＴ合并阿米替林对心境恶劣障碍的治疗效应。方法：将９５例患者随机分为三组，ＲＥＴ组２９例，阿米替林组３４例，合并治疗组３２例。采用Ｈａｍｉｌｔｏｎ和Ｚｕｎｇ氏抑郁量表进行治疗前后评定，用方差分析和均数ｔ检验。结果：ＲＥＴ合并阿米替林组对心境恶劣障碍的临床疗效、依从性优于ＲＥＴ及阿米替林组。结论：合并治疗组对心境恶劣障碍安全有效。
Objective: To explore the therapeutic effect of rational-emotional therapy (RET), amitriptyline and RET combined with amitriptyline on patients with dysthymia. Methods: Ninety-five patients were randomly divided into three groups: RET in 29 cases, Amitriptyline in 34 cases and combined treatment in 32 cases. Hamilton and Zung’s depression scale was used to assess before and after treatment, with analysis of variance and mean t-test. Results: The clinical efficacy of RET combined with amitriptyline in patients with dysthymia was better than those in RET and amitriptyline groups. Conclusion: The combined treatment group is safe and effective for the treatment of patients with dysthymia.