我院自1989年开始研制能在光纤内镜引导下进行插管的食管腔内可曲性冷冻探头,研制成功后体外实验空载探头的温度可达—197℃。于1991年开始进行临床研究和应用,用于治疗食管和贲门病变,现已完成70例,报告如下。 临床资料 男57例,女13例,年龄35～76岁,平均年龄55.6岁。70例中食管癌52例、贲门癌18例,术前均有细胞学或病理学的诊断。均以吞咽困难为主要临床症状。本文中吞咽困难的程度按照下列标准进行分级:0级,无吞咽困难;Ⅰ级,进普食有时发噎;Ⅱ级,进半流;Ⅲ级, Since 1989, our institute has begun to develop esophageal cavity flexible probes that can be intubated under the guidance of fiber optic endoscopes. After the successful development of the probes, the temperature of in-vitro probes can reach -197°C. Clinical research and application began in 1991 for the treatment of esophageal and cardiac lesions, and 70 cases have been completed. The report is as follows. Clinical data: 57 males and 13 females, aged 35-76 years, mean age 55.6 years. Among the 70 patients with esophageal carcinoma in 52 cases and cardiac cancer in 18 cases, there were cytology or pathological diagnosis before surgery. Dysphagia was the main clinical symptom. The degree of dysphagia in this article was graded in accordance with the following criteria: Grade 0, no dysphagia; Grade I, puerperal feeding sometimes flared; Grade II, half flow; Grade III,