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本文采用免疫组化及电镜观测分析了206例垂体腺瘤,根据激素分泌及超微结构特征将肿瘤分为11类.其中泌乳素腺瘤最常见(35.92%);其次是生长激素腺瘤(19.42%);零细胞腺瘤(16.50%)等.本文借助流式细胞术DNA分析研究了38例术后复发的垂体腺瘤后认为:嗜酸性干细胞腺瘤和伴Nelson综合征的促肾上腺皮质激素腺瘤有术后复发的倾向;此外,侵袭性生长的腺瘤和流式细胞术测定时DNA含量较高的DNA异倍体腺瘤的恶性度相对较高,术后易于复发.
In this study, 206 cases of pituitary adenomas were analyzed by immunohistochemistry and electron microscopy. According to hormone secretion and ultrastructural features, the tumors were divided into 11 categories. Among them, prolactinomas were the most common (35.92%); followed by growth hormone adenomas ( 19.42%); Zero cell adenomas (16.50%) et al. We studied 38 cases of postoperative recurrent pituitary adenomas by flow cytometry DNA analysis and thought that eosinophilic stem cell adenomas and adrenocortical with Nelson syndrome. Hormone adenomas have a tendency of recurrence after operation. In addition, invasive adenomas and DNA adenomas with higher DNA content when measured by flow cytometry have a higher degree of malignancy and are prone to recurrence.