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1971年1月—1974年1月间450例活动性肺结核住入某医院,最后确定22例并存肺癌(5％),均由枝气管镜、开胸或尸检确诊。肺结核尸检所见肺癌发病率高于常人之20倍,和大量吸烟人群相似。肺部慢性炎症和纤维变易癌变,结核病引起的肺实质疤痕刺激非典型上皮细胞增生和化生,以致恶变。本组病例中央型肺癌较周围疤痕癌为多见。
Between January 1971 and January 1974, 450 cases of active tuberculosis were admitted to a hospital, and finally 22 cases of lung cancer (5%) were confirmed, all of which were confirmed by bronchoscopy, thoracotomy or autopsy. The incidence of lung cancer seen in autopsy of pulmonary tuberculosis is 20 times higher than that of ordinary people, similar to that of a large number of smokers. Chronic lung inflammation and fibrosis susceptible to cancer, pulmonary tuberculosis caused by substantial scars stimulate atypical epithelial cell proliferation and metaplasia, resulting in malignant transformation. This group of patients with central lung cancer than the surrounding scar cancer is more common.