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目的 观察充血性心力衰竭 (CHF)病人心肌肌钙蛋白I(cTnI)的改变以及葛根素对cTnI的影响。方法 60例CHF病人随机分为常规治疗组和葛根素治疗组 ,两组疗程均为 2周。观察治疗前后cTnI以及左室射血分数、左室短轴缩短率、每搏输出量、每分输出量及心脏指数等指标变化情况。结果 经治疗 2周后 ,葛根素治疗组总有效率和显效率显著高于常规治疗组(P <0 .0 5 ) ;治疗后两组病人cTnI较治疗前显著降低 ,葛根素治疗组优于常规治疗组 (P <0 .0 5 )。结论 CHF病人存在cTnI异常 ,葛根素注射液可纠正CHF病人异常的cTnI水平。
Objective To observe the changes of cardiac troponin I (cTnI) in patients with congestive heart failure (CHF) and the effect of puerarin on cTnI. Methods 60 patients with CHF were randomly divided into conventional treatment group and puerarin treatment group, two courses of treatment were 2 weeks. Before and after treatment cTnI and left ventricular ejection fraction, shortening of left ventricular short axis, stroke volume, output per minute and cardiac index and other indicators changes. Results After 2 weeks of treatment, the total effective rate and markedly effective rate in the puerarin group were significantly higher than those in the conventional treatment group (P <0.05). After treatment, cTnI in both groups was significantly lower than that before treatment, and the puerarin-treated group was superior to The conventional treatment group (P <0.05). Conclusions There is cTnI abnormality in CHF patients. Puerarin injection can correct abnormal cTnI level in CHF patients.