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小柴胡汤(SST)广泛用于治疗各种感染性疾病如慢性病毒性肝炎,气管炎和普通感冒。干扰素α/β(IFNα/β)具有较强的抗病毒作用。日本学者曾设想将小柴胡汤和TFNα/β联合应用,然而这种联合用药治疗病毒性肝炎的可能性因其产生间质性肺炎的副作用而被否定。联合用药引起间质性肺炎的机理不甚清楚,可能涉及联合用药引起的过敏反应和(或)对免疫及炎症反应的药物协同怍用。
Xiao Chai Hu Tang (SST) is widely used to treat a variety of infectious diseases such as chronic viral hepatitis, bronchitis and the common cold. Interferon α / β (IFNα / β) has a strong antiviral effect. Japanese scholars have envisaged the combination of Xiao Chai Hu Tang and TFNα / β, however, the possibility of such combination therapy for the treatment of viral hepatitis is negated by the side effects of interstitial pneumonia. The mechanism of combination therapy causing interstitial pneumonia is unclear and may involve the combination of anaphylaxis and / or drugs for immune and inflammatory responses.