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目的分析宁夏银川、吴忠市儿童青少年血脂水平与血压的关系。方法采用分层整群随机抽样方法,于2013年9月在宁夏银川和吴忠市抽取学生2 331人,对其进行问卷调查、血压测定及血脂水平测定。结果研究对象高血压检出率为18.6%;不同年龄组儿童青少年高血压检出率差异有统计学意义(χ~2=116.186,P=0.000),10岁年龄组高血压检出率最高,为32.7%。不同年龄组血脂异常检出率及其水平有差异(均P<0.05),血脂异常组收缩压(SBP)、舒张压(DBP)水平均高于血脂正常组(P<0.001),低密度脂蛋白胆固醇(LDL-C)、总胆固醇(TC)高血压检出率异常组高于正常组,差异均有统计学意义(P<0.05);不同体质指数(BMI)水平下SBP、DBP水平差异均有统计学意义(P<0.01),高血压检出率肥胖组>超重组>正常组。进一步二元logistic回归分析结果表明,年龄(OR=0.754,90%CI=0.717~0.793)、高密度脂蛋白胆固醇(HDL-C)(OR=0.594,90%CI=0.424~0.832)、LDL-C(OR=1.550,90%CI=1.272~1.840)、甘油三酯(TG)(OR=1.733,90%CI=1.546~1.944)、TC(OR=1.502,90%CI=1.357~1.663)、BM I(OR=1.173,90%CI=1.134~1.213)、高血压家族史(OR=1.282,90%CI=1.050~1.660)均与高血压相关。结论儿童青少年高血压检出率处于较高水平,血脂可能是血压的影响因素,HDL-C是高血压的保护性因素,LDL-C、TG、TC、BMI、高血压家族史均是高血压的危险性因素。
Objective To analyze the relationship between blood lipid levels and blood lipid levels in children and adolescents in Yinchuan and Wuzhong of Ningxia. Methods A stratified cluster random sampling method was adopted. In September 2013, 2,331 students were sampled in Yinchuan and Wuzhong, Ningxia Province. Questionnaires, blood pressure and blood lipid levels were performed. Results The detection rate of hypertension was 18.6%. The detection rate of hypertension among children and adolescents in different age groups was significantly different (χ ~ 2 = 116.186, P = 0.000). The highest detection rate of hypertension was found in 10 years old group, Is 32.7%. The detection rate and level of dyslipidemia in different age groups were different (all P <0.05). The SBP and DBP levels in dyslipidemia group were significantly higher than those in normal lipids group (P <0.001) The levels of LDL-C and TC in the abnormal group were significantly higher than those in the normal group (P <0.05). The levels of SBP and DBP in different body mass index (BMI) (P <0.01). The detection rate of hypertension was obesity group> overweight group> normal group. The results of further binary logistic regression analysis showed that there were significant differences in age (OR = 0.754,90% CI = 0.717-0.793), HDL-C (OR = 0.594,90% CI = 0.424-0.832) (OR = 1.550,90% CI = 1.272-1.840), triglyceride (TG) (OR = 1.733,90% CI = 1.546-1.944), TC (OR = 1.502,90% CI = 1.357-1.663) BM I (OR = 1.173, 90% CI = 1.134-1.213), family history of hypertension (OR = 1.282, 90% CI = 1.050-1.660) were all associated with hypertension. Conclusion The prevalence of hypertension in children and adolescents is at a high level. Serum lipids may be the influencing factors of blood pressure. HDL-C is a protective factor of hypertension. The family history of hypertension, LDL-C, TG, TC, BMI, Dangerous factors.