Korngold 和Pressman 借助放射性核素标记抗体证明从实验动物制备的抗特异性动物肿瘤抗体含有肿瘤摄取的抗体。1957年,Pr-essman 等证明放射性碘标记抗体可供动物诊断应用,并且放射性核素显象可以定位摄取抗体之肿瘤。以后,Bale 等证明肿瘤定位(tum-or-localizing)抗体借助于自身的放射性可用作实验新生物的治疗剂。本文目的是复习放射 Korngold and Pressman used radionuclide labeled antibodies to demonstrate that anti-specific animal tumor antibodies prepared from experimental animals contained antibodies taken up by the tumor. In 1957, Pr-essman et al. demonstrated that radioactive iodine-labeled antibodies could be used for animal diagnostic applications, and that radionuclide imaging could localize tumors that take up antibodies. Later, Bale et al. demonstrated that tum-or-localizing antibodies can be used as therapeutic agents for experimental novel organisms by virtue of their own radioactivity. The purpose of this article is to review radiation