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目的分析医院胃肠道肿瘤患者围手术期临床诊治的相关资料,找出发生医院感染的原因,并制定相应的感染控制措施。方法将2009年1月-2013年1月在医院接受胃肠道肿瘤手术并在围手术期发生感染的90例患者作为感染组,同期的314例无感染患者作为对照组,找出导致胃肠道肿瘤围手术期临床诊治中发生感染的危险因素,并对其进行非条件logistic回归分析,找出独立危险因素,并通过查阅文献和临床经验找出控制感染的相关措施。结果胃肠道肿瘤围手术期临床诊治患者发生医院感染率为22.28%,经logistic回归分析显示,患有基础疾病(β=0.850,OR=5.123)、感染前有放化疗史(β=1.114,OR=6.517)、低蛋白血症(β=0.997,OR=5.835)、住院天数≥7d(β=0.907,OR=5.382)是导致胃肠道肿瘤围手术期临床诊治中感染发生的危险因素。结论胃肠道肿瘤围手术期临床诊治中感染率较高,易引发感染的危险因素较多,在临床工作中,应注意对危险因素的重视并合理预防,确保患者就医安全。
Objective To analyze the relevant data of perioperative clinical diagnosis and treatment of gastrointestinal cancer patients in hospitals, find out the causes of nosocomial infections, and formulate corresponding infection control measures. Methods From January 2009 to January 2013, 90 patients who underwent gastrointestinal tumor surgery in the hospital and were infected during the perioperative period were treated as the infection group. In the same period, 314 patients without infection were used as a control group to find out the cause of gastrointestinal tract. The risk factors for infection during clinical diagnosis and treatment of tumors in the perioperative period were analyzed, and unconditional logistic regression analysis was performed to find out independent risk factors. Related measures for controlling infections were found by consulting literature and clinical experience. Results The incidence of nosocomial infection in perioperative patients with gastrointestinal tumors was 22.28%. Logistic regression analysis showed that there were basic diseases (β=0.850, OR=5.123) and history of radiotherapy and chemotherapy before infection (β=1.114. OR=6.517), hypoalbuminemia (β=0.997, OR=5.835), length of hospital stay≥7d (β=0.907, OR=5.382) were risk factors for infection during perioperative clinical diagnosis and treatment of gastrointestinal cancer. Conclusion The infection rate of gastrointestinal cancer during perioperative period of clinical diagnosis and treatment is relatively high, and there are more risk factors for infection. In clinical work, attention should be paid to risk factors and reasonable prevention to ensure the safety of patients.