Safety and efficacy of complete versus near-complete coiling in treatment of intracranial aneurysms

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Objective: This study aimed to evaluate the clinical and angiographic outcomes of aneurysms that were completely or near-completely embolized and ascertain whether complete embolization is important in the stent-assisted coiling (SAC) of intracranial aneurysms.Methods: This retrospective study enrolled 390 patients (417 aneurysms).Among them,complete (100%) or nearcomplete (>90%) angiographic obliteration of the aneurysms on immediate angiography was accomplished.Baseline characteristics,complications,angiography follow-up results,and clinical outcomes were analyzed.Results: Cumulative adverse events occurred in 30 patients (7.7%),including thromboembolic complications in 17 (4.4%),intraoperative rupture in 10 (2.6%),and others in 3 (0.8%).Statistical analyses revealed an increased intraprocedural rupture rate in the initial completely occluded aneurysms (5.6% compared with 1.0%).The incidence of cumulative adverse events was higher in patients with completely occluded aneurysms (11.1%) than in those with near-completely occluded aneurysms (5.5%).Angiography follow-up was available for 173 aneurysms.Aneurysm occlusion status at follow-up was correlated with stent placement (p =0.000,odds ratio 5.847),size (p =0.000,odds ratio =6.446 for tiny aneurysms;and p =0.001,odds ratio =5.616 for small aneurysms),and initial aneurysm occlusion status (p =0.001,odds ratio =3.436).Complete occlusion at followup was seen in 82.6% of the initial complete occlusion group versus 63.0% of the initial near-complete occlusion group.The incidence of complete occlusion at follow-up was higher in the initial completely occluded aneurysms with SAC (100%) than in the initial completely occluded aneurysms with non-SAC (65.2%).Conclusions: Initial complete treatment may lead to higher complication rates and good clinical outcomes at follow-up.Stent placement may enhance progressive aneurysm occlusion.Initial complete occlusion with SAC can provide durable closure at follow-up.
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