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关于δ抗原抗体系统的研究进展,国内外已有专题综述,现仅就1982年以来有关本系统的几点新认识综述如下: 一、δ因子δ因子总是与乙型肝炎病毒(HBV)感染相关联,它是一种有缺陷的病毒样传染性因子,其复制需要有HBV合成。目前已知δ因子只有一个血清型。δ因子是由直径为35～37nm颗粒所组成,类似一种大的乙型肝炎小圆球状颗粒,与HBV具有共同的HBsAg外壳。δ因子的内部成分缺乏形态学特点,由δ抗原和一个很小的RNA分子(分子量约为500,000)所
As for the research progress of δ-antigen and antibody system, there are special reviews at home and abroad. Only a few new understandings on this system since 1982 are summarized as follows: 1, δ-factor δ-factor is always associated with hepatitis B virus (HBV) infection It is a defective virus-like infectious agent whose replication requires HBV synthesis. It is currently known that there is only one serotype of the delta factor. The delta-factor is composed of 35-37 nm in diameter particles, similar to a large, hemoglobin-globular particle with a common HBsAg envelope with HBV. The lack of morphological characteristics of the internal components of the δ-factor, caused by the δ antigen and a small RNA molecule (molecular weight of about 500,000)