目的探讨运用术前及术中MRI进行垂体腺瘤神经导航手术的作用。方法对44例垂体腺瘤患者于术前在导航系统工作站中进行MRI三维重建,制定出手术计划,标记重要结构。术中应用MRI导航定位并指导手术操作。结果所有MRI导航手术均获成功,术中神经导航定位精确,注册误差0-1.9mm。术后MRI复查肿瘤全切除者36例(81.9%)、次全切除者8例(18.1%)。结论神经外科手术导航系统是借助医学影像提供的信息提高手术的精度和安全性的一种技术手段;MRI是进行垂体腺瘤导航手术最适合的导航基础图像。 Objective To investigate the effect of preoperative and intraoperative MRI on neuroimaging of pituitary adenoma. Methods Forty - four patients with pituitary adenoma underwent MRI three - dimensional reconstruction in the navigation system workstation before operation, and a surgical plan was made to mark important structures. Intraoperative MRI navigation and guidance and surgical operation. Results All MRI navigation procedures were successful. The intraoperative neuro-navigation positioning was accurate with a registration error of 0-1.9mm. Thirty-six patients (81.9%) underwent total tumor resection after MRI, and 8 patients (18.1%) underwent subtotal resection. Conclusion Neurosurgery navigation system is a kind of technical means to improve the accuracy and safety of surgery with the information provided by medical imaging. MRI is the most suitable navigation basic image for navigation of pituitary adenoma.