新生儿持续性肺动脉高压(PPHN)病死率较高,目前尚无最佳治疗方法。本文介绍了用前列环素(prostacyclin,PGI_2)治疗PPHN的经验。 对象 随机选择赫尔辛基大学儿童医院8名PPHN患儿。男5例,女3例。其中呼吸窘迫综合症2例,胎粪吸入3例,肺出血1例,血液吸入1例,原发性PPHN1例。诊断标准包括:胎龄34～40周;出生体重>2500 Neonatal persistent pulmonary hypertension (PPHN) higher mortality, there is no optimal treatment. This article describes the experience of treating PPHN with prostacyclin (PGI_2). Subjects randomly selected eight Holstein Children’s Hospital PPHN children. 5 males and 3 females. Among them, 2 cases of respiratory distress syndrome, 3 cases of meconium aspiration, 1 case of pulmonary hemorrhage, 1 case of blood inhalation, 1 case of primary PPHN. Diagnostic criteria include: gestational age 34 to 40 weeks; birth weight> 2500