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超敏感性局部急性肺炎或外源性变应性肺泡炎的临床特点是,吸入各种抗原以后4～8小时出现咳嗽、发烧和呼吸困难。虽然已鉴定有许多抗原可引起这种综合征,但通常认为农民肺的综合征是由于吸入含嗜热性放线菌孢子的发霉干草粉尘所致。该病首次发现于1932年,直到1963年才有人认为嗜热性放线菌导致以上综合征,并指出患者血清中存在有抗发霉干草抗原的沉淀抗体。作者在美国怀俄明州西部一地区进行流行病
The clinical features of hypersensitivity to localized acute or extrinsic alveolitis are cough, fever and difficulty breathing 4 to 8 hours after inhalation of various antigens. Although many antigens have been identified as causing the syndrome, farmer lung syndrome is generally considered to be caused by inhalation of mildew dust containing thermophilic actinomycete spores. The disease was first discovered in 1932 and it was not until 1963 that it was thought that thermophilic actinomycetes caused the above syndrome and suggested the presence of precipitated antibodies against the moldy hay antigens in the patient’s serum. The author is endemic in a district in the western part of Wyoming, USA