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目的:评价化学发光微粒子免疫分析法(CMIA)和甲苯胺红不加热血清学试验(TRUST)在梅毒血清学筛选试验中的应用价值。方法:分别用CMIA方法和TRUST方法检测住院患者的血清标本共1 921例,并比较梅毒检测结果。结果:CMIA方法检出163例阳性,阳性率8.49%;TRUST方法检出131例阳性,阳性率6.82%,两者差异有统计学意义(P<0.05)。结论:CMIA方法较TRUST可以很大提高梅毒抗体检测的工作效率,其有漏检率低、操作简单方便、检测周期短、能批量检测等优点,可推荐为临床检验科梅毒血清学筛选试验的方法。
Objective: To evaluate the value of chemiluminescence microparticle immunoassay (CMIA) and toluidine red unheated serological test (TRUST) in serological screening of syphilis. Methods: A total of 1 921 serum samples from hospitalized patients were detected by CMIA and TRUST respectively, and the results of syphilis were compared. Results: The positive rate of CMIA was 163 cases (8.49%). The positive rate of TRITY was 131 cases (6.82%). The difference was statistically significant (P <0.05). CONCLUSION: Compared with TRUST, CMIA method can greatly improve the working efficiency of syphilis antibody detection. The CMIA method has the advantages of low missed detection rate, simple and convenient operation, short detection period and batch detection, and may be recommended as a clinical screening test for syphilis serological screening test method.