对溶组织内阿米巴非致病性虫株经过无菌培养可转变为致病性虫株这一现象的解释具有高度争议。实验选用NIH收集的溶组织内阿米巴分离株,无菌培养在含10％或15％牛血清的TYI-S-33培养基上的200:NIH株克隆2,其酶株群属于酶株群Ⅱ,而迪斯帕内阿米巴为NIH:0692:2株则属于酶株群Ⅰ,在含10％牛血清的IYI-S-33培养基上培养, The interpretation of the phenomenon that Entamoeba histolytica non-pathogenic strains can be transformed into pathogenic strains after aseptic culture is highly controversial. In the experiment, E. histolyticae isolates collected from NIH were selected and cultured in a 200: NIH clone 2 on a TYI-S-33 medium containing 10% or 15% bovine serum. The enzyme strains belonging to the enzyme strains Group II, while disiphenamidase was NIH: 0692: 2 strains belonging to enzyme group I, cultured in 10% bovine serum on IYI-S-33 medium,