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目的探讨不同恶性程度的乳腺肉瘤的诊疗方法及预后。方法收集齐齐哈尔医学院附属第三医院自1995年1月-2015年1月间收治的21例乳腺肉瘤患者的资料,整理病理类型、临床治疗及预后情况。结果 21例手术患者,病理诊断为叶状囊肉瘤17例,乳腺间质肉瘤3例,血管肉瘤1例。术后随访20年,死亡12例,其中3例为非肿瘤原因死亡。7例于不同时间出现肺或骨转移,最长出现转移时间为8年。术后化疗患者8年生存率22.2%,放疗患者8年生存率44.4%,未放、化疗患者8年生存率为55.6%。结论乳腺肉瘤的手术方式切缘范围较大,没有必要行腋窝淋巴结清除。若淋巴结转移广泛、肿瘤范围较大、可清除腋窝淋巴结,切除不彻底,可以放疗。对于已出现远处转移的,一般采用姑息化疗的方法治疗或对孤立的转移病灶给予切除,延长生存期。
Objective To investigate the diagnosis and treatment of breast cancer with different degrees of malignancy and its prognosis. Methods The data of 21 cases of breast sarcoma treated in the Third Affiliated Hospital of Qiqihar Medical College from January 1995 to January 2015 were collected and the pathological type, clinical treatment and prognosis were collected. Results 21 cases of surgical patients, pathological diagnosis of cystic sarcoma in 17 cases, 3 cases of breast stromal sarcoma, 1 case of angiosarcoma. The patients were followed up for 20 years and 12 died, of which 3 died of non-tumor. Seven cases had pulmonary or bone metastases at different times, and the longest time of metastasis was 8 years. The 8-year survival rate of postoperative chemotherapy was 22.2%, the 8-year survival rate of radiotherapy was 44.4%, and the 8-year survival rate of non-radiotherapy and chemotherapy was 55.6%. Conclusion Breast sarcoma surgical approach margin larger, there is no need axillary lymph node clearance. If a wide range of lymph node metastases, a larger tumor range, clear axillary lymph nodes, resection is not complete, you can radiotherapy. For those who have had distant metastases, palliative chemotherapy is generally used to treat or isolated metastatic lesions to give resection and prolong survival.