在动物模型中,癫痫可因自身免疫机理所致,癫痫病人可存在某种免疫异常。本文介绍国外应用大剂量免疫球蛋白治疗难治性儿童癫痫的方法和效果。提示免疫球蛋白作为治疗癫痫的措施,是一种可喜的尝试;其作用机理尚有待进一步探讨,可望在今后的临床应用中,获得更大的突破。 In animal models, epilepsy may be due to the mechanism of autoimmunity, epilepsy patients may have some kind of immune abnormalities. This article describes the foreign application of high-dose immunoglobulin treatment of refractory childhood epilepsy methods and results. Prompt immunoglobulin as a measure of treatment of epilepsy is a gratifying attempt; its mechanism of action remains to be further explored, is expected in the future clinical applications, access to greater breakthroughs.