1973年,Barnes等首先试用锌治疗肠病性肢端皮炎,以后很多作者陆续报告显效病例。最近,作者等对一例10岁男性和一例20岁女性患者,试用锌疗法,均取得明显疗效。两例患者内服氯碘喹治疗时,曾反复缓解和加重。治疗开始前的临床症状除缺乏腹泻外,其余都很典型。临床各项化验检查除血清锌值在20微克/公升以下(正常值66～100微克/公升,原子吸光法)外,其余都在正常范围内。血清锌等每周测定一次,硫 In 1973, Barnes and other first trial of zinc treatment of enterocolitis acral dermatitis, many authors later reported effective cases. Recently, the author of a 10-year-old man and a 20-year-old female patients, trial of zinc therapy, have achieved significant results. Two patients orally taking chloroquine therapy, had repeatedly alleviate and aggravate. Before the start of clinical symptoms except lack of diarrhea, the rest are typical. Clinical laboratory tests in addition to serum zinc values ​​below 20 micrograms / liter (normal 66 to 100 micrograms / liter, atomic absorption method), the rest are in the normal range. Serum zinc and other tests once a week, sulfur