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已证明,Leucotrofina(商品名)能减轻肿瘤化疗中的骨髓抑制,提高患者对病毒和细菌的抵抗力,并减少小儿哮喘的发作程度和次数;实验证明它可诱导正常或裸小鼠脾中前T 细胞成熟,使细胞表面出现免疫荧光可检测的Thy 1,2抗原。最近证明,牛胸腺提取物Lucotrofina 的有效成分是胸腺调节素(Thymomo-dulin),已获得高活性的纯化物。体外,试验证明,不同的胸调素制剂均能显著诱导脾细胞出现Thy 1.2膜抗原,其最适浓度为12.5μg.
Leucotrofin (trade name) has been shown to reduce myelosuppression in tumor chemotherapy, increase patient resistance to viruses and bacteria, and reduce the extent and frequency of asthma attacks in children; experiments have shown that it can induce normal or nude mice T cells mature, so that immunofluorescence can be detected on the cell surface Thy 1,2 antigen. Recently, it has been demonstrated that the active ingredient of bovine thymus extract Lucotrofina is Thymomo-dulin, and a highly active purified product has been obtained. In vitro, the experiment proved that different thymus preparations can significantly induce Thy 1.2 membrane antigen spleen cells, the optimal concentration of 12.5μg.