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目的探讨静脉注射造影剂对妇科肿瘤术后全盆腔放疗剂量分布的影响。方法选择10例接受术后全盆腔放疗的子宫内膜癌和子宫颈癌患者。对每例患者静脉注射造影剂前后相同体位下行CT模拟定位扫描,在平扫图像和增强图像上为每例患者设计相同的三维适形全盆腔放疗计划。比较两组计划靶区、危及器官和正常组织剂量分布。结果增强计划的靶区、危及器官和正常组织平均剂量均低于平扫计划,但两组计划间差异均<1.0Gy,危及器官和正常组织最大剂量差异均<2.0 Gy,差异均无统计学意义。结论静脉注射造影剂对妇科肿瘤术后全盆腔适形放疗剂量分布影响很小,临床上可以忽略。
Objective To investigate the effect of intravenous contrast medium on the dose distribution of pelvic radiotherapy after gynecologic oncology. Methods Ten patients with endometrial cancer and cervical cancer who received postoperative pelvic radiotherapy were selected. For each patient before and after intravenous contrast agent CT scan down the same position positioning scan, in the plain scan images and enhanced images for each patient to design the same three-dimensional conformal pelvic radiotherapy plan. Compare the planned target area of two groups, endanger the dose distribution of organs and normal tissues. Results The target dose, organ and normal tissue dose of the enhanced program were lower than that of the plain scan program, but the differences between the two groups were less than 1.0 Gy, the maximal doses of organs at risk and normal tissues were less than 2.0 Gy, and the differences were not statistically significant significance. Conclusion Intravenous injection of contrast agent has little effect on the dose distribution of pelvic conformal radiotherapy after gynecologic oncology. It can be neglected clinically.