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目的分析HIV单阳配偶孕前进行特定信息咨询、配偶告知、高效抗逆转录病毒治疗等综合干预对HIV单阳配偶间传播的影响。方法对广西自治区贺州市八步区2012-2013年有生育计划的HIV单阳配偶进行孕前综合干预自然受孕后随访检测1年(152对),回顾性分析该地区2010-2011年自然受孕分娩的HIV单阳配偶孕前综合干预情况(151对)。结果 2012-2013年HIV单阳配偶妊娠分娩后阴性配偶阳转0例,2010-2011年HIV单阳配偶妊娠分娩后阴性配偶阳转7例,差异有显著性(P≤0.05)。结论对有生育愿望的HIV单阳配偶进行孕前综合干预能有效降低HIV单阳配偶间传播。
Objective To analyze the influence of comprehensive intervention such as specific information consultation, spouse notification and highly effective antiretroviral therapy on the transmission of HIV single positive mate before HIV single male mate. Methods A total of 152 pairs of HIV-positive males were recruited from HIV-positive mate with reproductive plan in Babu District, Hezhou City, Guangxi Autonomous Region for 2012-2013. The patients were followed up for 1 year after natural conception (152 pairs) HIV single male spouse before pregnancy comprehensive intervention (151 pairs). Results In 2012-2013, there were 0 cases of negative spouse positive transfer of HIV maternal pregnancy after delivery. In 2010-2011, 7 cases of negative maternal positive transfer of HIV maternal pregnancy after delivery were found significant difference (P≤0.05). Conclusions The pre-pregnancy pre-treatment intervention for HIV single male spouse with fertility desire can effectively reduce the transmission of HIV single male spouse.