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产科DIC的发生率约占分娩数的0.1%,其中50~60%发生在胎盘早期剥离的患者,从子痫和胎盘早期剥离死亡孕妇的尸解所见,显示妊高征和DIC有密切关系。一般临床上把妊高征并发DIC作为妊高征患者病象的一部份,主要是由于患者循环血液中血液凝固因子的消耗速度比肝脏的再生速度快,引起凝血因子减少。临床表现为血小板减少,血小板功能低下;抗凝血酶Ⅲ(AT—Ⅲ)减少;纤维蛋白原减少;a_2血纤维蛋白溶酶抑制物(a_2PI)减少;血和尿中纤维蛋白
The incidence of obstetric DIC accounted for about 0.1% of the number of births, of which 50 to 60% occurred in patients with early placental exfoliation, eclampsia and early placental exfoliation of pregnant women from the autopsy findings showed that PIH and DIC are closely related . Clinically, PIH as a part of PIH patients is mainly due to the consumption of blood coagulation factors in patients with circulating blood faster than the liver regeneration, causing reduced clotting factor. Clinical manifestations of thrombocytopenia, platelet dysfunction; antithrombin Ⅲ (AT-Ⅲ) decreased; decreased fibrinogen; a_2 reduced serum plasminogen (a_2PI); blood and urine fibrin