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目前认为,支气管哮喘是一种由嗜酸细胞引起的气道炎症。此类炎症致气道可逆性阻塞和对非特异刺激呈高反应性。炎症过程决定哮喘发作程度和发展,因此,现代治疗重点已转向抗炎治疗。发病机理和临床过敏性炎症过程分即刻反应和延迟反应。局部被激活的嗜酸细胞释放嗜酸细胞阳离子蛋白(ECP)、碱基蛋白(MBP)等细胞毒性蛋白和氧活性
At present, bronchial asthma is a type of airway inflammation caused by eosinophils. Such inflammation causes reversible obstruction of the airways and is highly reactive with non-specific stimuli. The inflammatory process determines the extent and development of asthma attacks, therefore, the focus of modern therapy has turned to anti-inflammatory treatment. Pathogenesis and clinical allergic inflammation in the immediate reaction and delayed response. Locally activated eosinophils release cytotoxic proteins such as eosinophil cationic protein (ECP), base protein (MBP) and oxygen activity