出血是各型急性白血病(acute leukemia,AL)重要的临床表现,也是白血病患者死亡的重要原因之一。赵征等[1]对AL患者的口腔健康状况进行统计,牙龈出血的发生率占第一位,仅次于皮肤出血或瘀斑。所以,有效控制AL牙龈出血对降低白血病出血的病死率及控制感染都具有重要意义。近三年 Bleeding is an important clinical manifestation of various types of acute leukemia (AL), and is also one of the important causes of death of leukemia patients. Zhao Zheng et al [1] on the oral health status of patients with AL statistics, the incidence of bleeding gums accounted for the first place, second only to skin hemorrhage or ecchymosis. Therefore, the effective control of bleeding AL gingival bleeding to reduce the mortality of leukemia and control of infection are of great significance. Nearly three years