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目的:分析脑转移瘤诊疗中存在的问题,以提高其治疗效果。方法:回顾性分析我院收治的脑转移瘤70例。结果:70例脑转移瘤中孤立性转移瘤34例,多发性转移瘤36例。肺癌尤其是肺腺癌是脑转移瘤的主要来源。肿瘤的脑转移不仅发生于肿瘤晚期,也发生于肿瘤早期。结论:①手术加放疗是目前孤立性脑转移瘤的主要治疗手段,立体定向放射外科是多发性脑转移瘤的治疗趋势;②血脑屏障及肿瘤多药耐受性是影响脑转移瘤化疗的主要因素。
Objective: To analyze the existing problems in the diagnosis and treatment of brain metastases in order to improve its therapeutic effect. Methods: A retrospective analysis of 70 cases of brain metastases admitted to our hospital. Results: Among 70 brain metastases, 34 were solitary metastases and 36 were multiple metastases. Lung cancer, especially lung adenocarcinoma, is a major source of brain metastases. Brain metastases of tumors occur not only in the advanced stages of the tumor, but also in the early stages of the tumor. Conclusion: ① Surgery plus radiotherapy is the main treatment of solitary brain metastases, stereotactic radiosurgery is the treatment of multiple brain metastases; ② blood-brain barrier and tumor multi-drug resistance is the impact of brain metastases chemotherapy major factor.