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青光眼目前仍是世界上主要的致盲眼病,其发病机制尚不清楚。直到最近,治疗青光眼的所有手段仍有赖于降低眼内压。近年来发现,热休克蛋白(heatshock protein,HSP)27在青光眼的视网膜神经节细胞(RGC)中过度表达,而其自身抗体具有促RGC凋亡的作用。临床上,青光眼尚无特效治疗手段
Glaucoma is still the leading cause of blindness in the world and its pathogenesis is still unclear. Until recently, all means of treating glaucoma still depended on reducing intraocular pressure. In recent years, heat shock protein 27 (HSP27) is overexpressed in retinal ganglion cells (RGCs) of glaucoma and its autoantibodies have the effect of promoting RGC apoptosis. Clinically, there is no effective treatment for glaucoma