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十多年来,我国城乡广泛服用脊髓灰质炎糖丸活疫苗,使脊髓灰质炎的发病率有了显著下降。但我国领土辽阔,地形复杂,气候多种多样。黑龙江北部全年无夏,海南岛长夏无冬,淮河流域四季分明,冬季南北温差颇大。在各种气候条件下疫苗免疫效果如何,我国过去研究不多。为了解脊髓灰质炎糖丸活疫苗在亚热带地区的免疫效果及肠道病毒感染对免疫效果的影响,我们于1973年冬在广东省海南琼山县进行了服苗后的病毒学及血清学调查。海南岛位子北纬18～20度,属亚热带气候区。现将结果报告如下:
For more than a decade, the poliovirus live vaccine has been widely used in urban and rural areas in China, causing a significant drop in the incidence of poliomyelitis. However, China has a vast territory, complex terrain and a variety of climates. No summer in northern Heilongjiang, Hainan Island long summer no winter, the Huaihe River Basin four seasons, winter temperature difference between north and south quite. In a variety of climate conditions, the effect of vaccine immunization, our country in the past few studies. In order to understand the immune effect of poliovirus live vaccine in subtropics and the effect of enterovirus infection on the immune effect, we carried out the virological and serological investigation after taking the vaccine in Qiongshan County, Hainan Province in the winter of 1973 . Hainan Island latitude 18 ~ 20 degrees, a subtropical climate zone. The results reported below: