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为探讨HBsAg患者的免疫状况,测定了30例HBSAg阳性儿童的T淋巴细胞亚群、B细胞及免疫球蛋白含量。结果显示:所有病例免疫球蛋白、B细胞与对照组相比无显著差异(P>0.05);有12例T细胞总数降低,抑制性T细胞增高,4例表现为T细胞总数降低。提示HBsAg阳性儿童细胞免疫功能的状况在病情的发展中起主导作用。
To investigate the immune status of patients with HBsAg, T lymphocyte subsets, B cells and immunoglobulin contents were measured in 30 HBSAg-positive children. The results showed that immunoglobulin and B cells in all cases had no significant difference compared with the control group (P> 0.05). The total number of T cells in 12 cases decreased and the number of inhibitory T cells increased in 4 cases, while the total number of T cells decreased. Tip HBsAg-positive children’s cellular immune function in the disease plays a leading role in the development.