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目的:评价系统性红斑狼疮(SLE)患者外周血中前白蛋白与超敏C反应蛋白的水平及意义。方法:SLE患者48例,活动组25例,非活动组23例,对照组25例。血清前白蛋白采用免疫透射比浊法,超敏C-反应蛋白采用散射免疫比浊法。结果:活动组血清前白蛋白检测结果较非活动组偏低具有统计学差异(P<0.01),且与狼疮活动呈负相关(P<0.05)。患者活动组超敏C-反应蛋白检测结果较非活动组偏高但无统计学意义(P>0.05)。结论:血清前白蛋白可以用来评价系统性红斑狼疮疾病活动。
Objective: To evaluate the level and significance of prealbumin and high sensitivity C-reactive protein in peripheral blood of patients with systemic lupus erythematosus (SLE). Methods: 48 cases of SLE patients, 25 cases of active group, 23 cases of inactive group and 25 cases of control group. Pre-serum albumin using immunoturbidimetric turbidimetric method, high-sensitivity C-reactive protein using immune turbidimetry. Results: Pretreatment serum albumin test results showed that there was a statistically significant difference (P <0.01), and was negatively correlated with lupus activity (P <0.05). Patients with active high-sensitivity C-reactive protein test results were higher than the inactive group but no significant difference (P> 0.05). Conclusion: Pre-serum albumin can be used to evaluate the disease activity of systemic lupus erythematosus.