论文部分内容阅读
熊胆为贵重中药材,来源不同,质量差异很大。其质量优劣以中国药典77年版,分为“金胆”、“铁胆”、“菜花胆”三种,以金胆为上品。模拟天然熊胆而研制的人工熊胆,是以“金胆”为质量依据的。人工熊胆含有各种氨基酸,微量元素,各种胆汁酸,胆固醇和胆红素。其质量特征是含有牛磺熊去氧胆酸(TUDCA)钠,牛磺鹅去氧胆酸(TCDCA)钠,TUDCA与TCDCA是差向异构体,同时存在。本文用薄层扫描谱、核磁共振谱、红外光谱和导数光谱等现代分析方法,对人工熊胆、天然熊胆和引流熊胆进行了综合光谱分析比较,认为其质量与天然熊胆(金胆)接近,优于引流熊胆。
Bear bile is a valuable Chinese herbal medicine, with different sources and different quality. Its quality is based on the 77th edition of the Chinese Pharmacopoeia, which is divided into three categories: “gold gall,” “iron gall,” and “cauliflower gall.” The artificial bear bile developed by simulating natural bear bile is based on the quality of “gold gall”. Artificial bear bile contains various amino acids, trace elements, various bile acids, cholesterol and bilirubin. Its quality characteristics are that it contains sodium tauroursodeoxycholic acid (TUDCA), taurochenodeoxycholic acid (TCDCA) sodium, and TUDCA and TDCCA are epimers that exist simultaneously. In this paper, synthetic analysis of artificial bear gallbladder, natural bear gallbladder and drained bear gall bladder was carried out by modern analytical methods such as thin-layer scanning spectroscopy, nuclear magnetic resonance spectroscopy, infrared spectroscopy, and derivative spectroscopy. The quality and natural bear bile (gold gall ) Closer, better than draining bear bile.