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藤黄酸(以下简称“736—2”)是中药藤黄的主要成分之一。临床应用(静脉注射或局部外用)对乳腺癌、宫颈癌、恶性淋巴瘤、皮肤癌等有一定疗效。灌服“736—2”对肉瘤18(以下简称 S180)腹水型无显著影响。腹腔注射“736—2”对 S180实体型无效,对其腹水型有明显抑制作用,但不能延长荷瘤动物的寿命,相反的还有所缩短。有的认为“736—2”对肿瘤细胞有选择性杀伤作用。为了进一步分析“736—2”对 S180的作用,进行
Gambogic acid (hereinafter referred to as “736-2”) is one of the main components of traditional Chinese medicine garcinia. Clinical application (intravenous or topical) has a certain effect on breast cancer, cervical cancer, malignant lymphoma, skin cancer, and the like. Oral administration of “736-2” had no significant effect on sarcoma 18 (hereinafter referred to as S180) ascites type. Intraperitoneal injection of “736-2” had no effect on the S180 solid type, but it had a significant inhibitory effect on its ascites type, but it could not prolong the life span of the tumor-bearing animals, but on the contrary it was shortened. Some believe that “736-2” has a selective killing effect on tumor cells. In order to further analyze the role of “736-2” on S180,