从细柱五加(Acanthopanax gracilistylus W．W．Smith)叶的热MeOH提取液中分离得到了4个lupane型三萜化合物,根据它们的理化性质和波谱数据,鉴定出其化学结构分别为acankoreagenin(1), 3-epi-betulinic acid 28-O-α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester(2),acantrifoside A(3)和acankoreoside C(4)．其中化合物1是首次从天然植物中分离得到的新化合物,化合物2是首次从五加科植物中分离得到的化合物,且这4个化合物都是第一次从细柱五加中分离得到． Four lupane-type triterpenoids were isolated from the hot MeOH extract of Acanthopanax gracilistylus W.W. Smith, and their chemical structures were identified as acankoreagenin ( 1) 3-epi-betulinic acid 28-O-α-Lhamnopyranosyl- (1 → 4) -β-D-glucopyranosyl- (1 → 6) 3) and acankoreoside C (4). Among them, compound 1 was isolated from natural plants for the first time. Compound 2 was the first compound isolated from plants of Gailou, and the four compounds were isolated for the first time.