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我院曾遇到绒毛膜癌转移至脾脏自发性破裂大出血一例,现报告如下: 26岁,于1983年12月30日自然分娩一活婴。5天后开始畏寒、发热,下腹疼痛,少量不规则阴道流血入院,诊刮组织活检为绒毛膜癌,经检查未发现转移。第十二天行子宫全切术,术中探查盆腔无转移,但未探查脾脏,病理检查为子宫绒毛膜癌。术后8天开始使用5-Fu1000mg/日化疗。3天后病人出现咳嗽并痰中带血,胸片报告为绒癌肺转移。经化疗一疗程及对症治疗,一般情况好,咳嗽咯血停止,无其他不适,伤口一期愈合出院。 2月后来院化疗,全身检查及妇查均未发现异常。胸透所见与第一次检查比较基本相同,合绒癌肺转移又用5-Fu1000mg/日治疗,4月24日
In our hospital, we encountered a case of choriocarcinoma metastasis to spontaneous splenic hemorrhage in the spleen. The report is as follows: 26 years old, born on December 30, 1983. After 5 days, chills, fever, abdominal pain, a small amount of irregular vaginal bleeding were admitted to the hospital, and the curettage tissue biopsy was chorionic carcinoma. No metastasis was found after examination. On the twelfth day, hysterectomy was performed. During the operation, no pelvic metastasis was detected, but the spleen was not explored. The pathological examination was choriocarcinoma. The 5-Fu 1000 mg/day chemotherapy was started 8 days after surgery. Three days later, the patient developed cough and bloody sputum. The chest radiograph was reported as choriocarcinoma lung metastasis. After a course of chemotherapy and symptomatic treatment, the general situation was good, coughing hemoptysis stopped, no other discomfort, the wound healed and discharged one time. After chemotherapy in the hospital in February, no abnormalities were found in the whole body examination and the woman’s examination. Chest radiography is basically the same as the first examination. Hemocarcinoma lung metastasis is treated with 5-Fu1000mg/day, April 24th.