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应用放射性同位素診断胃癌,主要依据是增生迅速的肿瘤组織对磷~(32)的吸收和代謝均增加,磷~(32)在肿瘤组織內聚集量較周围正常组織为多。1952年Cramer和Pabst报告胃癌部位所含磷~(32)的浓度比其周围正常组織高,其測定方法是令病人咽下一个小型盖革計数器(Geiger Counter),然后在透視下将計数器操纵在所要測定的部位,进行放射性計数来診断胃癌。根据洗胃液內磷~(32)排出百分率来診断胃癌。Clode发现胃癌组織积聚放射性碘~(131)較周围正常组織多,因此提出了利用放射性碘~(131)体外扫描法診断胃癌。Robert在检查前18～20小时給病人靜
The use of radioisotopes for the diagnosis of gastric cancer is mainly based on the rapid increase of tumor tissue absorption and metabolism of phosphorus (32), and the accumulation of phosphorus (32) in the tumor tissue is more than the surrounding normal tissue. In 1952 Cramer and Pabst reported that the site of stomach cancer contains more phosphorus-32 than normal surrounding tissue. The method of measurement is to make the patient swallow a small Geiger counter and then count under the perspective. The device is operated at the site to be measured and radioactivity is counted to diagnose gastric cancer. Gastric cancer was diagnosed based on the percentage of phosphorus-(32) excreted in gastric lavage fluid. Clode found that gastric cancer tissue accumulation of radioactive iodine ~ (131) more than the surrounding normal tissue, so the use of radioactive iodine ~ (131) in vitro scan diagnosis of gastric cancer. Robert gives the patient 18 to 20 hours before the examination