Laurence-Moon-Biedl综合征临床上少见,我院遇见1例,现报告如下。患者女,14岁。因自幼夜盲,并随年龄增长而逐年加剧,且智力低下,于1984年10月9日就诊我院。父母为姑表兄妹结婚,现存弟1人,无类似病史。体检:表情淡漠,小老头外观。体重21kg,身高121cm,头围48.5cm,胸围54cm,指间距114cm。光感性皮炎,面部四肢皮肤呈光泽样苔癣。头发稀疏, Laurence-Moon-Biedl syndrome clinically rare, I met 1 hospital, are as follows. Female patient, 14 years old. Because of his childhood night blindness, and with age and increasing year by year, and mental retardation, on October 9, 1984 visit our hospital. Parents cousins ​​married, one of the existing brother, no similar medical history. Physical examination: expression of indifference, little old man appearance. Weight 21kg, height 121cm, head circumference 48.5cm, chest circumference 54cm, finger spacing 114cm. Photodermatitis, facial skin was glossy lichen planus. Thinning hair,